Project information
RECETOX RI - OP VVV
(RECETOX RI)
- Project Identification
- CZ.02.1.01/0.0/0.0/16_013/0001761
- Project Period
- 1/2017 - 6/2021
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Operational Programme Research, Development and Education
- Priority axis 1: Strengthening capacities for high-quality research
- MU Faculty or unit
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Faculty of Science
- prof. RNDr. Jana Klánová, Ph.D.
- Mgr. Lenka Bahulová
- Mgr. Ondřej Bouša
- PhDr. Jan Cacek, Ph.D.
- Hale Demirtepe, PhD.
- RNDr. Veronika Eclerová, Ph.D.
- Mgr. Marta Gimunová, Ph.D.
- prof. RNDr. Jakub Hofman, Ph.D.
- MDDr. Julie Horáková, Ph.D.
- Mgr. Petr Huta
- prof. MUDr. Lydie Izakovičová Hollá, Ph.D.
- Ing. Mgr. Jana Juříková, Ph.D.
- prof. RNDr. Jana Klánová, Ph.D.
- Mgr. Jiří Kohoutek, Ph.D.
- Eva Kolbová
- Bc. Martina Kolomazníková
- Mgr. Lenka Kosečková Micenková, Ph.D.
- Mgr. et Mgr. Daniela Kuruczová, Ph.D.
- Mgr. Jan Kuta, Ph.D.
- Mgr. Petra Labohá, Ph.D.
- doc. Mgr. Lenka Lacinová, Ph.D.
- prof. Gerhard Lammel, PhD.
- prof. PhDr. Petr Macek, CSc.
- Mgr. Zuzana Masopustová, Ph.D.
- Mgr. Petra Pátková Daňsová, Ph.D.
- Maria Persico, PhD
- MUDr. Jitka Pikhartová, M.Sc., Ph.D.
- doc. Ing. Vlad Popovici, PhD
- Karla Andrea Pozo, PhD.
- RNDr. Petra Přibylová, Ph.D.
- Tatsiana Rusina, Ph.D.
- Mgr. et Mgr. Dana Seryjová Juhová
- Foppe Smedes
- Mgr. Lenka Svobodová, Ph.D.
- doc. RNDr. Zdeněk Šimek, CSc.
- Mgr. Lucia Škulcová, Ph.D.
- Mgr. Jan Švancara
- MUDr. Iva Tomášková, Ph.D.
- Ing. Tomáš Vodička, Ph.D.
- Ing. Martina Vodičková
- doc. Ing. Branislav Vrana, PhD.
- prof. Mgr. Martin Zvonař, Ph.D.
- Keywords
- research infrastructure, population studies, biomonitoring of toxic compounds, sampling methods
This project focuses on an important interdisciplinary area of research linking environmental pollution and human health. Research in this border area is crucial for addressing current societal challenges such as quality of life, aging population or food safety. The aging population and the increasing incidence of some diseases have been identified as an important societal problem with an impact on the economy and subsequently reflected in European and national priorities.
An increasing need to monitor the occurrence of these specific diseases (neurodegenerative disorders, allergic diseases, immune disorders, metabolic disorders) in the population, depending on their environmental, social and economic determinants (socioeconomic situation, nutrition, lifestyle, alcohol and drug abuse, exposure to toxic substances) emphasizes the importance of large population studies. These studies must, however, be linked to the best available methods and technologies in the relevant research areas (analytical chemistry and biochemistry, toxicology, risk analysis, biostatistics, modelling, epidemiology). The RECETOX RI project contributes to the building of unique expertise across biomedical, environmental and social sciences and information technologies.
The aim of the project is to maintain the cutting-edge quality of environmental research carried out in the RECETOX centre and to extend it to new competitive research areas promising to increase the social impact of this research and to produce results with future application potential. This will be achieved by (i) building a new capacity for long-term archiving of environmental and human samples equipped with technology for their safe and sustainable storage, (ii) the development of a set of top sampling and analytical methods necessary for the implementation of such research, (iii) further development of large- studies providing answers to major societal issues, and (iv) building expertise on long-term population studies that link data on environmental and human exposure to human health data. The project provides financial support from EU funds.
Results
20211: Odborné publikace (vybrané typy dokumentů) vytvořené podpořenými subjekty - 54 publikací, 20216: Odborné publikace (vybrané typy dokumentů) se zahraničním spoluautorstvím vytvořené podpořenými subjekty - 23 publikací, 20312: Počet účastí podpořených výzkumných týmů realizovaných v programech mezinárodní spolupráce - 1
Publications
Total number of publications: 218
2023
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Cerebral organoids derived from patients with Alzheimer´s disease with PSEN1/2 mutations have defective tissue patterning and altered development
CELL REPORTS, year: 2023, volume: 42, edition: 11, DOI
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Embedding nonlinear systems with two or more harmonic phase terms near the Hopf–Hopf bifurcation
Nonlinear Dynamics, year: 2023, volume: 111, edition: 2, DOI
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Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration
MOLECULAR ONCOLOGY, year: 2023, volume: 17, edition: 4, DOI
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Occurrence, source estimation, and risk assessment of Polycyclic Aromatic Hydrocarbons in coastal seawaters from the Quintero Industrial Complex (Valparaiso, Chile)
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Plastic debris, persistent organic pollutants and their toxicity impacts in coastal areas in Central Chile
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Using real-time ascertainment rate estimate from infection and hospitalization dataset for modeling the spread of infectious disease: COVID-19 case study in the Czech Republic
2022
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Current use pesticides in soil and air from two agricultural sites in South Africa: Implications for environmental fate and human exposure
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Emergency cesarean section is a risk factor for depressive symptoms when breastfeeding is limited
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Maternal gender discrimination and child emotional and behavioural problems: A population-based, longitudinal cohort study in the Czech Republic
EClinicalMedicine, year: 2022, volume: 53, edition: November 2022, DOI
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Multicompartmental analysis of POPs and PAHs in Concepcion Bay, central Chile: Part I - Levels and patterns after the 2010 tsunami