Metabolický syndrom a dětský věk
| Title in English | Metabolic Syndrome and Childhood |
|---|---|
| Authors | |
| Year of publication | 2013 |
| Type | Chapter of a book |
| MU Faculty or unit | |
| Citation | |
| Description | Obesity, hypertension, diabetes mellitus and dyslipidemia are the most frequent diseases in economically developed countries, including the Czech Republic. This complex of abnormalities consists of the Reaven's metabolic syndrome (MS), resp. insulin resistance syndrome. MS is a combination of risk factors accelerating the development of atherosclerosis and manifestation of the type 2 diabetes (DM2T), and thus significantly increases cardiovascular morbidity and mortality. Some medical specialist companies (eg. IDF) published a diagnostic parameters MS for children and adolescents, based on the definitions of MS for adults. An important diagnostic procedure is therefore, similar to the adult figure of waist circumference, which is significantly related to the insulin resistance. The prevalence of MS in obese children varies depending on the stringency of the criteria used, between 18-50 %. Conversely, in children with optimal body weight is MS detected at less than 1%. In addition to the basic components of MS there can be found MS complications in children that were not previously known, such as nonalcoholic fatty liver disease (NAFLD). Therapy is chosen according to the degree of seriousness of obesity and according to the age of the child. However, the basic treatment procedure of metabolic risk factors in childhood is intervention on lifestyle, ie . modification of obesity causing eating habits and increase of physical activity . In the indicated cases, there is used pharmacotherapy (antiobesity drugs, metformin) or bariatric surgery procedures. Currently, some experts questioned the term metabolic syndrome in childhood due to the fact that all components of the MS (in particular obesity, hypertension, insulin resistance) are reversible in childhood. Particular emphasis is laid on the prevention, diagnosis and treatment of various well-defined risk factors for premature atherosclerosis, which are considered separate clinical entities. |
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