Autonomní nervový systém, metabolický syndrom a pohybová aktivita

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Title in English Autonomic nervous system, metabolic syndrome and physical activity.


Year of publication 2014
MU Faculty or unit

Faculty of Sports Studies

Description Autonomic imbalance, characterized by predominance sympathetic activity over parasympathetic activity, is associated with metabolic syndrome. The altered balance of the parasympathetic and sympathetic nervous activity contributes to the development of hypertension, obesity, insulin resistance, type 2 diabetes mellitus or dyslipoproteinemia, can lead to premature aging and may be a final common pathway to increased morbidity and mortality. Model of autonomic imbalance may provide a unifying framework within which can be investigate the impact of risk factors on cardiovascular disease. Spectral analysis of heart rate variability (HRV) may be highly used to assess autonomic imbalances. HRV generally is markedly reduced in patients with metabolic syndrome and the complex parameters of spectral analysis of HRV are often associated with individual metabolic syndrome risk factors. Decreased HRV also precedes the development of a number of risk factors. Conversely, lowering risk profiles is associated with increased HRV. Regular and appropriate intensive physical activity increases the autonomic nervous system activity and shifts the autonomic control of the heart toward vagal dominance. Therefore, physical activity represents a valuable strategy to counter chronic disease-related impairments of cardiac autonomic activity. The association between modifiable risk factors and markers for autonomic function suggest possible physical activity interventions that may improve health of subjects with metabolic syndrome.
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