Souvislost genetických faktorů s rozvojem kardiovaskulárních onemocnění u sportovců

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Title in English Connection of genetic factors with the development of cardiovascular diseases in sportsmen
Authors

JÍRA Miroslav VYSOKÝ Robert VOMELOVÁ Naděžda VOMELA Jindřich ZÁVODNÁ Eva

Year of publication 2010
Type Article in Periodical
Magazine / Source Medicina Sportiva Bohemica Slovaca
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords training; cardiovascular diseases; polymorphism A1166C; AT1 receptor; polymorphismus T-786C and G894T; eNOS
Description The aim of this study was to evaluate the association of polymorphisms in genes pivotal for cardiovascular diseases with hemodynamic parameters (BRS, BPV) and point at possible risk factors for development of these diseases in sportsmen. A significant association of the studied polymorphism with monitored parameters was found. In active sportsmen, carriers of critical allels, their influence on alteration of cardiovascular system regulation, adaptation mechanisms and cardiovascular diseases development could be exerted.
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